After fire superintendent Jake Carson (John Cena) and his elite team of expert firefighters (Keegan-Michael Key, John Leguizamo and Tyler Mane) rescue three young siblings — Bryn (Brianna Hildebrand), Will (Christian Convery) and Zoey (Finley Rose Slater) from a burning home, they're unable to locate the children's parents.

With no option other than to watch over the children until their parents can be found, Jake makes them promise to behave so the firefighters can do their jobs. Unfortunately, the children are undisciplined and quickly take over the fire depot with their antics.