Set 25 years after the original, sisters Sally (Sandra Bullock) and Gillian (Nicole Kidman) face a dangerous new crisis tied to the origins of their magic. When Sally's daughter (Joey King) uncovers long-buried secrets and begins to develop dark, unpredictable abilities, the family is thrust into a multi-generational struggle to end their ancestral curse.

Sally, Gillian and their aunts (Stockard Channing, Dianne Wiest) must reunite and journey from Massachusetts to the United Kingdom, where their magic began, to confront its source. As past and present collide, they risk everything to finally break the curse and protect future generations from its deadly legacy.